منابع مشابه
The action of streptomycin.
Previous papers (Umbreit, 1949; Oginsky, Smith, and Umbreit, 1949) have presented data showing that one of the actions of streptomycin on a sensitive Escherichia coli strain was to inhibit the oxalacetate-pyruvate reaction. It was admitted that the exact nature of this reaction was not known and that methods for its measurement were somewhat indirect. At about the time these papers were publish...
متن کاملStreptomycin Action and Anaerobiosis.
The question was asked whether the insensitivity to dihydrostreptomycin and streptomycin exhibited by facultatively anaerobic organisms growing strictly anaerobically could be due entirely to the lack of an anaerobic mechanism for the uptake of these antibiotics. A technique is described here which allows exposure of Escherichia coli B to dihydrostreptomycin, under conditions which are known to...
متن کاملA site of action of streptomycin.
Various reports (l-5) have demonstrated that streptomycin inhibits the metabolic activities of the non-proliferating cells of susceptible strains of bacteria. This paper is an attempt to trace the mode of action of streptomycin with the object of determining what reactions vital to the cell are interfered with. Study of the mode of action of the antibiotics of therapeutic value should eventualI...
متن کاملAction of streptomycin on Vibrio cholerae.
Arora & Krishna Murti (1955) showed that broadspectrum antibiotics inhibit oxygen uptake by Vibrio cholerae cells in the presence of the tricarboxylic acid-cycle intermediates, but have no perceptible effect on the corresponding oxidations in animal-tissue homogenates. The availability of a V. cholerae strain sensitive to streptomycin and a resistant mutant derived from it has made it possible ...
متن کاملA Site of Action of Streptomycin
Various reports (l-5) have demonstrated that streptomycin inhibits the metabolic activities of the non-proliferating cells of susceptible strains of bacteria. This paper is an attempt to trace the mode of action of streptomycin with the object of determining what reactions vital to the cell are interfered with. Study of the mode of action of the antibiotics of therapeutic value should eventualI...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1949
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.58.6.747-759.1949